ProgramIndicationsDiscoveryPreclinicalPhase 1Phase 2
EP262
MRGPRX2
Antagonist
Chronic Spontaneous Urticaria (CSU)
 
 
  Chronic Inducible Urticaria (CindU)
 
 
  Atopic Dermatitis (AD)
 
 
  Other Indications
 
 
EP547
MRGPRX4
Antagonist
Cholestatic Pruritus (CP)
 
 
  Uremic Pruritus (UP)
 
 
  Other Indications
 
 
MRGPRD Undisclosed
 
 
MRGPRX1 Undisclosed
 
 
MRGPRX2 Antagonist (EP262)
DiscoveryPreclinicalPhase 1Phase 2

Chronic Spontaneous Urticaria (CSU)

Chronic Inducible Urticaria (CindU)

Atopic Dermatitis (AD)

Other Indications

MRGPRX4 Antagonist (EP547)
DiscoveryPreclinicalPhase 1Phase 2

Cholestatic Pruritus (CP)

Uremic Pruritus (UP)

Other Indications

MRGPRD
DiscoveryPreclinicalPhase 1Phase 2

Undisclosed

X1
DiscoveryPreclinicalPhase 1Phase 2

Undisclosed

All of Escient’s programs are wholly-owned.